Medical Leadership

The Physicians Behind At Your Best

Our approach is shaped by nationally and internationally recognized clinicians at the frontier of brain health, neuroscience, longevity, and translational medicine.

RG Portrait coming soon

Dr. Robert G. Bota MD, MSG, DFAPA

Chief Medical Officer

  • Founder & Medical Director, Brain Health Solutions

Dr. Robert G. Bota is a nationally recognized psychiatrist, researcher, educator, and physician executive whose career has been dedicated to advancing the science of brain health, mental performance, longevity, and innovative medical treatments. With more than 25 years of clinical, academic, and research experience, Dr. Bota has established himself as one of the leading voices in modern psychiatry and integrative brain optimization.

As Chief Medical Officer of At Your Best Human Performance Institute, Dr. Bota brings a unique combination of evidence-based psychiatry, neuroscience, performance medicine, and longevity-focused healthcare. His vision is to help individuals not only overcome illness but achieve optimal cognitive, emotional, and physical performance through personalized, science-driven medical care.

Dr. Bota earned his Doctor of Medicine degree from the Carol Davila University of Medicine and Pharmacy in Bucharest, Romania. He pursued advanced postgraduate training in the United States, earning a Master of Science in Gerontology from the University of Southern California before completing his Psychiatry Residency and serving as Chief Resident at the University of Missouri–Kansas City School of Medicine.

Board-certified in Psychiatry by the American Board of Psychiatry and Neurology, Dr. Bota has spent decades at the forefront of academic medicine and clinical innovation, with faculty leadership at UC Irvine and UC Riverside, where he achieved the rank of Clinical Professor of Psychiatry and Human Behavior. He has authored more than 60 scientific publications and book chapters and delivered over 100 presentations at national and international conferences.

In 2019, he founded Brain Health Solutions, a psychiatric and neuroscience center recognized for Transcranial Magnetic Stimulation (TMS), Spravato® therapy, and clinical research. He pioneered the first TMS program at UC Irvine after advanced neuromodulation training at Harvard University and the University of South Carolina, and serves as Principal Investigator in numerous clinical trials. His contributions earned him the distinction of Distinguished Fellow of the American Psychiatric Association (DFAPA).

At At Your Best, Dr. Bota integrates neuroscience, hormone optimization, metabolic health, regenerative medicine, longevity science, and cognitive enhancement to help patients unlock their highest levels of health, resilience, and performance — guided by the belief that medicine should maximize human potential, not simply treat disease.

DA Portrait coming soon

Dr. Daniela A. Bota MD, PhD

Chief Scientific Advisor

  • Vice Dean for Clinical Research, UC Irvine School of Medicine
  • Director, UCI Alpha Stem Cell Clinic

Dr. Daniela A. Bota is an internationally recognized physician-scientist, neuro-oncologist, clinical researcher, and medical innovator whose groundbreaking work has helped advance the treatment of some of the most challenging diseases affecting the human brain. As Chief Scientific Advisor for At Your Best Human Performance Institute, she provides scientific leadership across brain health, longevity medicine, regenerative therapies, neuroscience, and human performance optimization.

A board-certified neurologist and neuro-oncologist, Dr. Bota has dedicated her career to bridging the gap between laboratory discovery and clinical application — transforming emerging breakthroughs into real-world treatments that improve both lifespan and healthspan while advancing the understanding of cognitive performance, neurological resilience, and regenerative medicine.

Born and educated in Romania, she earned her Doctor of Medicine degree from the Carol Davila University of Medicine and Pharmacy in Bucharest. She earned a PhD in Molecular Biology from the University of Southern California, completed Neurology residency at the University of Kansas Medical Center, and a competitive Neuro-Oncology fellowship at Duke University Medical Center.

She holds numerous leadership positions within the University of California system, including Vice Dean for Clinical Research at the UC Irvine School of Medicine, Professor of Neurology, Director of the UCI Alpha Stem Cell Clinic, Clinical Director of the Sue & Bill Gross Stem Cell Research Center, and Medical Director of the UCI Health Comprehensive Brain Tumor Program.

Internationally recognized for her expertise in brain cancer, Dr. Bota specializes in primary and metastatic brain tumors, glioblastoma, and advanced neurotherapeutics. She has served as principal investigator for numerous FDA-regulated clinical trials involving cellular therapies, cancer vaccines, targeted oncology agents, and regenerative medicine, and has authored or co-authored more than 200 peer-reviewed publications, book chapters, and abstracts.

Her honors include multiple Orange County Medical Association Physician of Excellence awards, Orange Coast Magazine Top Doctor recognition, the UCI Dean’s Physician Award, and National Cancer Institute clinician awards. At At Your Best, she brings scientific rigor, clinical excellence, and visionary thinking — ensuring every innovation the Institute pursues is grounded in the highest standards of medical research and patient safety.

By invitation only

Start Your Optimization Journey

Care guided by medical insight.

Eligibility for At Your Best begins with a private consultation reviewed by our medical team. Access is by invitation and application.